Tag Archive for ‘national clinical trials’


Gastric cancer: Recent updates in surgical and multimodality therapy

Recently completed and ongoing clinical trials in resectable gastric cancer are summarized.

Figure 1. Overall schema of ALCHEMIST

In search of the philosopher’s stone: The ALCHEMIST study for lung cancer

This month’s column provides an update on the ALCHEMIST trials for patients with operable lung cancer, including the addition of a third arm to study, which permits the inclusion of patients without ALK or EGFR mutations.

Figure 1. A021302: Impact of early FDG-PET directed intervention in locally advanced gastric cancer

A new approach for advanced gastric cancer: Using PET scans as a biomarker of preoperative chemotherapy efficacy

This month’s column describes how new technology may improve outcomes for patients diagnosed with gastric cancer, specifically the use of PET scans as a biomarker of preoperative chemotherapy efficacy.

Positron emission tomography with the glucose analog fluorine-18 FDG studies in patients with clinically responding and nonresponding tumors (© 2003 American Society of Clinical Oncology).

Studies address metabolic image-directed oncologic therapy for gastric cancer

Research findings regarding the effect of metabolic response on gastric cancer are summarized, including the new Alliance 021302 trial.

TME specimen

Rectal cancer resection: Laparoscopic or open—which way forward?

The primary outcome of the Z6051 rectal cancer trial is outlined in this month’s column as are new surgical trial concepts that resulted from this study.

Progress in the PROSPECT trial: Precision treatment for rectal cancer?

The PROSPECT trial for individualized treatment is discussed in this month’s column as is the surgeon’s role in ensuring the success of this trial.

Community-based physicians and hospitals need to participate in clinical trials

Enrolling patients into national clinical trials—particularly patients from community cancer centers—is necessary to advance the science and treatment of cancer care.


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