Tag Archive for ‘ductal carcinoma in situ’

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Active surveillance as a treatment modality in ductal carcinoma in situ

Because many cases of ductal carcinoma in situ (DCIS) may remain stable without excision, more clinical trials are exploring the role of active surveillance in DCIS management.

FIGURE 1. COMET Trial Schema

Surgery versus monitoring and endocrine therapy for low-risk DCIS: The COMET Trial

The COMET Trial—a prospective randomized study aimed at assessing the risks and benefits associated with active surveillance versus guideline concordant care for patients with low-risk ductal carcinoma in situ—is the focus of this month’s column.

CALGB 40903: Phase II single-arm study of neoadjuvant letrozole for ER(+) postmenopausal DCIS

Reframing treatment for ductal carcinoma in situ: Could less be more?

In a typical breast surgery practice, nearly one-fifth of new patients present with ductal carcinoma in situ (DCIS), usually detected on mammography as an incidental finding. Most of these women are otherwise healthy, take care of themselves, have had a mammogram as part of their routine health maintenance, and are now grappling with a “cancer” […]


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