Tag Archive for ‘clinical trials’

ACS CRP

Ga-68 imaging changes clinical management of GI and pancreatic neuroendocrine tumors

Ga-68 positron emission tomography has improved the clinical management of gastrointestinal and pancreatic neuroendocrine tumors, and multiple studies are ongoing to define its optimal role in clinical practice.

 

From Residency to Retirement

Databases: Where math meets medicine

Balancing statistical relevance with clinician experience leads to innovative approaches to patient care.

The evolution of lung cancer surgery contributes to the sharpest drop in overall cancer mortality in the U.S.

The evolution of lung cancer surgery contributes to the sharpest drop in overall cancer mortality in the U.S.

This article describes the advancements in early detection and surgical treatment of lung cancer that led to improved lung cancer survival from a thoracic surgeon’s perspective.

ACS CRP

Early-stage prostate cancer decision aids for diverse patient populations

The aim of the Alliance A191402CD trial is to evaluate the use of decision aids for men choosing treatment for located prostate cancer, particularly in minority populations.

ACS Clinical Research Program

What is the National Clinical Trials Network, and how do I join?

A summary of the structure and function of the National Cancer Institute’s National Clinical Trial Network is provided.

ACS CRP

Modified FOLFIRINOX is superior to gemcitabine as adjuvant therapy for resected pancreatic cancer: The PRODIGE 24/CCTG PA6 Trial

The study design and findings of the PRODIGE 24/CCTG PA6 Trial are outlined, which showed improved survival with modified FOLFIRINOX for resected pancreatic cancer patients.

Figure 1. Schema: ALCHEMIST CHEMO-IO

ALCHEMIST trial has potential to improve outcomes after lung cancer resection

The ALCHEMIST CHEMO-IO is a trial for patients with early-stage non-small cell lung cancer (NSCLC) with the potential to change the way patients with resected NSCLC are treated.

ACS CRP

Could axillary reverse mapping be useful in reducing surgical comorbidities?

A summary of some of the research that evaluates the role of axillary reverse mapping in cancer patients.

ACS CRP

Evolution in the management of desmoid tumors: Challenging the role of upfront surgical resection

Describes the traditional management of desmoid tumors as well as new approaches, including radiation therapy for locally aggressive tumors.

ACS CRP

Opportunities at Clinical Congress 2019 to increase surgeon participation in clinical research

The ACS CRP will offer sessions at Clinical Congress 2019 on the topics of developing clinical trial and decreasing administrative burden associated with those trials.

ACS CRP

Defining the optimal treatment of locally advanced gastric cancer

Clinical trial data are examined to help develop a consensus approach for locally advanced gastric cancer.

Preoperative smoking intervention techniques improve outcomes for lung cancer patients

Smoking cessation intervention trials examine potential outcome improvements for lung cancer patients.

ACS CRP

Atezolizumab in the adjuvant treatment of stage III colon cancer: Can PD-L1 inhibition improve survival?

The study design for the ATOMIC trial (Alliance A021502), a randomized phase III study examining atezolizumab treatment of stage III colon cancer, is described.

ACS CRP

Robotic surgery for hepatic neoplasms: Where does it fit in the minimally invasive surgery landscape?

This month’s column identifies prospective clinical trials aimed at clarifying the role of laparoscopic and robotic surgery for hepatic neoplasms.

NCDB logo

Active surveillance as a treatment modality in ductal carcinoma in situ

Because many cases of ductal carcinoma in situ (DCIS) may remain stable without excision, more clinical trials are exploring the role of active surveillance in DCIS management.

ACS CRP

Immunotherapy in solid tumors

The role of precision immunotherapy in treating solid tumors is summarized.

ACS CRP

Clinical trials for surgeons: Hurdles and opportunities

An educational program developed jointly by the ACS CRP and the Society of Surgical Oncology provides surgeons with the tools they need to actively participate in clinical trials

Figure 1. Mechanism of checkpoint blockade

Current role of immunotherapy in urologic cancers

The role of immunotherapy in the treatment of urologic cancers is summarized and the efficacy of novel immunotherapeutics, particularly checkpoint inhibitors, are described, which may hold promise for a wide variety of tumor types.

ACS CRP

Gastrectomy for cancer: What are the benefits of a minimally invasive approach?

Gastric cancer is a significant cause of cancer morbidity and mortality in the U.S., with an estimated 26,370 new cases and 10,730 deaths in 2016.1 The incidence of gastric cancer is rising, particularly proximal tumors, and among young (< 40 years old) Caucasians, who have experienced a nearly 70 percent increase in the incidence of […]

ACS CRP

ACS CRP Dissemination and Implementation Committee issues call for participants in pilot project

The mission of the Dissemination and Implementation Committee—to provide surgeons with practice-changing results of the Alliance and other national clinical trial groups—is summarized.

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