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How successful is NST in increasing breast-conserving surgery rates in TNBC patients?(Comments Off on How successful is NST in increasing breast-conserving surgery rates in TNBC patients?)

April 1, 2016

Historically, neoadjuvant systemic therapy (NST) has been mainly used to convert breast cancer from inoperable to operable; however, today NST also is incorporated into the treatment of patients who initially present with operable disease. NST can allow some patients with stage II-III breast cancer who initially present with disease extent necessitating mastectomy to possibly undergo […]

Dissemination and implementation: Translating cancer guidelines and clinical trial outcomes into everyday practice

Dissemination strategies and implementation research programs, which examine how clinical trials data may be incorporated into clinical use, are the focus of this month’s column.

TME specimen

Rectal cancer resection: Laparoscopic or open—which way forward?

The primary outcome of the Z6051 rectal cancer trial is outlined in this month’s column as are new surgical trial concepts that resulted from this study.

Figure 1. SWOG S1316 Schema

Prospective comparative effectiveness trial for malignant bowel obstruction: SWOG S1316

The aim and approach of the Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction trial is the focus of this month’s column.

Response to preoperative endocrine therapy in breast cancer patients can alter surgical and chemotherapy options

The uptake of neoadjuvant endocrine therapy in the U.S. has been slow according to the authors of this month’s column, even though this treatment can reduce the extent of breast surgery.


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