ACS Clinical Research Program
The past decade has seen a paradigm shift in the treatment of men with advanced prostate cancer, according to the authors of this month column, a result of improved understanding of disease biology, investment in basic research and identification of rational therapeutic targets, collaboration with industry, and design and completion of well-designed clinical trials.
The Patient-Centered Outcomes Research Institute has awarded three research funding contracts to the ACS Cancer Research Program of the Alliance for Clinical Trials in Oncology with the goal of developing a more patient-centered and individualized approach to post-treatment surveillance of colorectal, breast, and lung cancers.
The ACS Oncology Group Z1071 trial and sentinel lymph node surgery in clinically node-positive patients receiving neoadjuvant chemotherapy are examined in this month’s column.
The rationale for neoadjuvant therapy is explored in this month’s column along with a summary of Alliance clinical trials involving this treatment.
Surgical quality of life questions can be an important part of assessing the impact of changes in treatment and, therefore, can play a significant role in prospective clinical trials.
More in this category
- Community-based physicians and hospitals need to participate in clinical trials
- Less invasive option for small hepatocellular carcinoma: Thermal ablation as first-line therapy?
- Patient-centered outcomes research: Is this really something new?
- Does altering diet affect progression of prostate cancer? The MEAL study
- American College of Surgeons Commission on Cancer Rapid Quality Reporting System: From quality measurement to quality improvement
- Improving cancer care through quality measures: Putting evidence to work with the CoC
- What is the appropriate extent of lymphadenectomy for bladder cancer?
- Are older adults adequately represented in surgical oncology trials?
- Borderline resectable pancreatic cancer: Pushing the technical limits of surgery
- Multiple ipsilateral breast cancers: Can the breast be preserved?
- Malignant pleural effusion research provides insights to improve surgical study design
- The paradox of breast MRI: Does finding occult disease make a difference?
- Announcing the Surgical Standards Manual Project: A call for volunteers
- What’s new in renal cell carcinoma
- The clinically negative axilla: The dilemma of occult metastases in sentinel nodes